preparation | benzyl anthranilate is prepared as follows: the mixture of indigo anhydride (8.54g), benzyl alcohol (6.0g), 4-dimethylaminopyridine (6.7g), dimethylformamide (17ml), triethylamine (5.28g) and dichloromethane (160ml) is refluxed overnight and washed with equal volume of ethyl acetate, water, salt water and water. The organic solution was dried with magnesium sulfate, filtered, and concentrated in vacuum. The crude product was purified by rapid chromatography and eluted with hexane solution 30% ethyl acetate to obtain the desired product. |